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The Bdnf Val68 to Met Polymorphism Increases Compulsive Alcohol Drinking In Mice Which Is Reversed By TrkB Activation
BACKGROUND: The Val66 to Met polymorphism within the brain-derived neurotrophic factor (BDNF) sequence reduces activity-dependent BDNF release, and is associated with psychiatric disorders in humans. Alcoholism is one of the most prevalent psychiatric diseases. Here, we tested the hypothesis that th...
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| Publicado no: | Biol Psychiatry |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4676961/ https://ncbi.nlm.nih.gov/pubmed/26204799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.06.007 |
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