The Opposing Roles of IVS2+691 CC Genotype and AC/AG Diplotype of 118A>G and IVS2+691G>C of OPRM1 Polymorphisms in Cold Pain Tolerance Among Opioid-Dependent Malay Males on Methadone Therapy

INTRODUCTION: We recently reported that a majority of opioid-dependent Malay males on methadone therapy are cold pain sensitive. It is postulated that common OPRM1 polymorphisms may be responsible. This study investigated the association between 118A>G (dbSNP rs1799971) and IVS2+691G>C (dbSNP...

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Vydáno v:Pain Ther
Hlavní autoři: Zahari, Zalina, Lee, Chee Siong, Ibrahim, Muslih Abdulkarim, Musa, Nurfadhlina, Yasin, Mohd Azhar Mohd, Lee, Yeong Yeh, Tan, Soo Choon, Mohamad, Nasir, Ismail, Rusli
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Healthcare 2015
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676768/
https://ncbi.nlm.nih.gov/pubmed/26581429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40122-015-0041-y
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