The AC/AG Diplotype for the 118A>G and IVS2 + 691G>C Polymorphisms of OPRM1 Gene is Associated with Sleep Quality Among Opioid-Dependent Patients on Methadone Maintenance Therapy

INTRODUCTION: Methadone is a full agonist of the opioid receptor mu 1 which is encoded by the OPRM1 gene. Sleep disorders were frequently reported by opioid-dependent patients during methadone maintenance therapy (MMT). It is possible, therefore, that genetic polymorphisms in OPRM1 influence sleep q...

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Detalhes bibliográficos
Publicado no:Pain Ther
Main Authors: Zahari, Zalina, Lee, Chee Siong, Ibrahim, Muslih Abdulkarim, Musa, Nurfadhlina, Mohd Yasin, Mohd Azhar, Lee, Yeong Yeh, Tan, Soo Choon, Mohamad, Nasir, Ismail, Rusli
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912965/
https://ncbi.nlm.nih.gov/pubmed/26792136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40122-016-0044-3
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