Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor

The melanocortin 1 receptor gene (MC1R) expressed in melanocytes is a major determinant of skin pigmentation. It encodes a Gs protein-coupled receptor activated by α-melanocyte stimulating hormone (αMSH). Human MC1R has an inefficient poly(A) site allowing intergenic splicing with its downstream nei...

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Vydáno v:PLoS One
Hlavní autoři: Herraiz, Cecilia, Olivares, Conchi, Castejón-Griñán, Maria, Abrisqueta, Marta, Jiménez-Cervantes, Celia, García-Borrón, José Carlos
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676704/
https://ncbi.nlm.nih.gov/pubmed/26657157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144757
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