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Effect of oral N-acetylcysteine on COPD patients with microsatellite polymorphism in the heme oxygenase-1 gene promoter

BACKGROUND: Heme oxygenase-1 (HO-1) plays a protective role as an antioxidant in the lung, and HO-1 gene promoter polymorphism has been shown to be associated with the severity and prognosis of COPD patients. N-acetylcysteine (NAC), an antioxidant/mucous modifier, has shown an uncertain benefit in C...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zhang, Jia-Qiang, Zhang, Jian-Qing, Fang, Li-Zhou, Liu, Ling, Fu, Wei-Ping, Dai, Lu-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676509/
https://ncbi.nlm.nih.gov/pubmed/26674585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S91823
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