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Heme Oxygenase-1 microsatellite polymorphism and haplotypes are associated with the development of acute respiratory distress syndrome

OBJECTIVE: Heme oxygenase-1 (HO-1) acts in cytoprotection against acute lung injury. The polymorphic (GT)n repeat in the HO-1 gene (HMOX1) promoter regulates HMOX1 expression. We investigated the associations of HMOX1 polymorphisms with ARDS risk and plasma HO-1 levels. DESIGN: Unmatched, nested cas...

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Detalhes bibliográficos
Main Authors: Sheu, Chau-Chyun, Zhai, Rihong, Wang, Zhaoxi, Gong, Michelle N., Tejera, Paula, Chen, Feng, Su, Li, Thompson, B. Taylor, Christiani, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758618/
https://ncbi.nlm.nih.gov/pubmed/19526221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-009-1504-6
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