A dual role of transient receptor potential melastatin 2 channel in cytotoxicity induced by silica nanoparticles

Silica nanoparticles (NPs) have remarkable applications. However, accumulating evidence suggests NPs can cause cellular toxicity by inducing ROS production and increasing intracellular Ca(2+) ([Ca(2+)](i)), but the underlying molecular mechanism is largely unknown. Transient receptor potential melas...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Yu, Peilin, Li, Jin, Jiang, Jialin, Zhao, Zunquan, Hui, Zhaoyuan, Zhang, Jun, Zheng, Yifan, Ling, Daishun, Wang, Lie, Jiang, Lin-Hua, Luo, Jianhong, Zhu, Xinqiang, Yang, Wei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676061/
https://ncbi.nlm.nih.gov/pubmed/26656285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18171
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