Zinc Inactivates Melastatin Transient Receptor Potential 2 Channels via the Outer Pore

Zinc ion (Zn(2+)) is an endogenous allosteric modulator that regulates the activity of a wide variety of ion channels in a reversible and concentration-dependent fashion. Here we used patch clamp recording to study the effects of Zn(2+) on the melastatin transient receptor potential 2 (TRPM2) channe...

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Detalhes bibliográficos
Principais autores: Yang, Wei, Manna, Paul T., Zou, Jie, Luo, Jianhong, Beech, David J., Sivaprasadarao, Asipu, Jiang, Lin-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129160/
https://ncbi.nlm.nih.gov/pubmed/21602277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.247478
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