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Molecular determinants of blood–brain barrier permeation

The blood–brain barrier (BBB) is a microvascular unit which selectively regulates the permeability of drugs to the brain. With the rise in CNS drug targets and diseases, there is a need to be able to accurately predict a priori which compounds in a company database should be pursued for favorable pr...

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Bibliografiske detaljer
Udgivet i:Ther Deliv
Main Authors: Geldenhuys, Werner J, Mohammad, Afroz S, Adkins, Chris E, Lockman, Paul R
Format: Artigo
Sprog:Inglês
Udgivet: Future Science Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675962/
https://ncbi.nlm.nih.gov/pubmed/26305616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/tde.15.32
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