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Erroneous Silencing of the Mitotic Checkpoint by Aberrant Spindle Pole-Kinetochore Coordination

To segregate chromosomes during cell division, microtubules that form the bipolar spindle attach to and pull on paired chromosome kinetochores. The spindle assembly checkpoint (SAC) is activated at unattached and misattached kinetochores to prevent further mitotic progression. The SAC is silenced af...

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Bibliografski detalji
Izdano u:Biophys J
Glavni autori: Chen, Jing, Liu, Jian
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675864/
https://ncbi.nlm.nih.gov/pubmed/26636952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.024
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