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Erroneous Silencing of the Mitotic Checkpoint by Aberrant Spindle Pole-Kinetochore Coordination

To segregate chromosomes during cell division, microtubules that form the bipolar spindle attach to and pull on paired chromosome kinetochores. The spindle assembly checkpoint (SAC) is activated at unattached and misattached kinetochores to prevent further mitotic progression. The SAC is silenced af...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biophys J
Päätekijät: Chen, Jing, Liu, Jian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675864/
https://ncbi.nlm.nih.gov/pubmed/26636952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.024
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