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NKT cell modulates NAFLD potentiation of metabolic oxidative stress-induced mesangial cell activation and proximal tubular toxicity

Obesity and nonalcoholic fatty liver disease (NAFLD) are associated with the development and progression of chronic kidney disease. We recently showed that NAFLD induces liver-specific cytochrome P-450 (CYP)2E1-mediated metabolic oxidative stress after administration of the CYP2E1 substrate bromodic...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Alhasson, Firas, Dattaroy, Diptadip, Das, Suvarthi, Chandrashekaran, Varun, Seth, Ratanesh Kumar, Schnellmann, Rick G., Chatterjee, Saurabh
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675804/
https://ncbi.nlm.nih.gov/pubmed/26447219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00243.2015
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