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Skp1 Independent Function of Cdc53/Cul1 in F-box Protein Homeostasis
Abundance of substrate receptor subunits of Cullin-RING ubiquitin ligases (CRLs) is tightly controlled to maintain the full repertoire of CRLs. Unbalanced levels can lead to sequestration of CRL core components by a few overabundant substrate receptors. Numerous diseases, including cancer, have been...
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| Publicado no: | PLoS Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4675558/ https://ncbi.nlm.nih.gov/pubmed/26656496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005727 |
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