Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway.

In normal and transformed cells, the F-box protein p45(SKP2) is required for S phase and forms stable complexes with p19(SKP1) and cyclin A-cyclin-dependent kinase (CDK)2. Here we identify human CUL-1, a member of the cullin family, and the ubiquitin-conjugating enzyme CDC34 as additional partners o...

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Detalhes bibliográficos
Main Authors: Lisztwan, J, Marti, A, Sutterlüty, H, Gstaiger, M, Wirbelauer, C, Krek, W
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170388/
https://ncbi.nlm.nih.gov/pubmed/9430629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.2.368
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