Protein Kinase C-Independent Inhibition of Organic Cation Transporter 1 Activity by the Bisindolylmaleimide Ro 31-8220

Ro 31–8220 is a potent protein kinase C (PKC) inhibitor belonging to the chemical class of bisindolylmaleimides (BIMs). Various PKC-independent effects of Ro 31–8220 have however been demonstrated, including inhibition of the ATP-binding cassette drug transporter breast cancer resistance protein. In...

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Publicat a:PLoS One
Autors principals: Mayati, Abdullah, Bruyere, Arnaud, Moreau, Amélie, Jouan, Elodie, Denizot, Claire, Parmentier, Yannick, Fardel, Olivier
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675551/
https://ncbi.nlm.nih.gov/pubmed/26657401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144667
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