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Fluorescent Probes for Tracking the Transfer of Iron–Sulfur Cluster and Other Metal Cofactors in Biosynthetic Reaction Pathways

Iron–sulfur (Fe–S) clusters are protein cofactors that are constructed and delivered to target proteins by elaborate biosynthetic machinery. Mechanistic insights into these processes have been limited by the lack of sensitive probes for tracking Fe–S cluster synthesis and transfer reactions. Here we...

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Pubblicato in:J Am Chem Soc
Autori principali: Vranish, James N., Russell, William K., Yu, Lusa E., Cox, Rachael M., Russell, David H., Barondeau, David P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675328/
https://ncbi.nlm.nih.gov/pubmed/25478817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja510998s
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