Incorporation of subject-level covariates in quantile normalization of miRNA data

BACKGROUND: Most currently-used normalization methods for miRNA array data are based on methods developed for mRNA arrays despite fundamental differences between the data characteristics. The application of conventional quantile normalization can mask important expression differences by ignoring dem...

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Foilsithe in:BMC Genomics
Main Authors: Suyundikov, Anvar, Stevens, John R., Corcoran, Christopher, Herrick, Jennifer, Wolff, Roger K., Slattery, Martha L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2015
Ábhair:
Methodology Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675058/
https://ncbi.nlm.nih.gov/pubmed/26653287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2199-4
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