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Alzheimer’s in 3D culture: Challenges and perspectives

Alzheimer’s disease (AD) is the most common cause of dementia, and there is currently no cure. The “β-amyloid cascade hypothesis” of AD is the basis of current understanding of AD pathogenesis and drug discovery. However, no AD models have fully validated this hypothesis. We recently developed a hum...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioessays
Hauptverfasser: D'Avanzo, Carla, Aronson, Jenna, Kim, Young Hye, Choi, Se Hoon, Tanzi, Rudolph E., Kim, Doo Yeon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674791/
https://ncbi.nlm.nih.gov/pubmed/26252541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500063
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