HuR mediated post-transcriptional regulation as a new potential adjuvant therapeutic target in chemotherapy for pancreatic cancer

AIM: To investigate the expression of HuR in pancreatic ductal adenocarcinoma (PDA) and to assess the effects of HuR silencing on the expression of cyclooxygenase-2 (COX-2) and heme oxygenase-1 (HO-1) and the in vitro response to gemcitabine (GEM) treatment in pancreatic cell lines. METHODS: We comp...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:World J Gastroenterol
Päätekijät: Jakstaite, Aldona, Maziukiene, Aurelija, Silkuniene, Giedre, Kmieliute, Kristina, Gulbinas, Antanas, Dambrauskas, Zilvinas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Baishideng Publishing Group Inc 2015
Aiheet:
Basic Study
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674719/
https://ncbi.nlm.nih.gov/pubmed/26675757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i46.13004
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