Polymorphisms of BCL2 and BAX Genes Associate with Outcomes in Advanced Non-small cell lung cancer Patients treated with platinum-based Chemotherapy

Single-nucleotide polymorphisms (SNP) of the gene belonging to the BCL2 family are thought to play a role in chemotherapy resistance. This study investigated the association of BCL2-938C>A(rs2279115) and BAX-248G>A(rs4645878) promoter region SNPs and the clinical responses and outcomes of 235...

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Pubblicato in:Sci Rep
Autori principali: Peng, Yu, Wang, Linang, Qing, Yi, Li, Chongyi, Ren, Tao, Li, Qing, Li, Mengxia, Zhang, Shiheng, Shan, Jinglu, Wang, Ge, Yang, Zhenzhou, Wang, Dong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674711/
https://ncbi.nlm.nih.gov/pubmed/26656462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17766
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