Treatment with PPARα Agonist Clofibrate Inhibits the Transcription and Activation of SREBPs and Reduces Triglyceride and Cholesterol Levels in Liver of Broiler Chickens

PPARα agonist clofibrate reduces cholesterol and fatty acid concentrations in rodent liver by an inhibition of SREBP-dependent gene expression. In present study we investigated the regulation mechanisms of the triglyceride- and cholesterol-lowering effect of the PPARα agonist clofibrate in broiler c...

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Detalhes bibliográficos
Publicado no:PPAR Res
Main Authors: Zhang, Lijun, Li, Chunyan, Wang, Fang, Zhou, Shenghua, Shangguan, Mingjun, Xue, Lina, Zhang, Bianying, Ding, Fuxiang, Hui, Dequan, Liang, Aihua, He, Dongchang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674622/
https://ncbi.nlm.nih.gov/pubmed/26693219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/347245
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