Autoimmune Hepatitis in Brazilian Children: IgE and Genetic Polymorphisms in Associated Genes

Pediatric autoimmune hepatitis (AIH) patients present hypergammaglobulinemia, periportal CD8(+) cytotoxic T cell infiltration, and cirrhosis. Autoantibody profile defines AIH types 1 and 2 in addition to strong association with HLA-DRB1. We previously detected increased IgE serum levels and sought t...

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Udgivet i:J Immunol Res
Main Authors: de Oliveira, Léa Campos, Goldberg, Anna Carla, Marin, Maria Lucia Carnevale, Schneidwind, Karina Rosa, Frade, Amanda Farage, Kalil, Jorge, Miura, Irene Kasue, Pugliese, Renata Pereira Sustovich, Danesi, Vera Lucia Baggio, Porta, Gilda
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674601/
https://ncbi.nlm.nih.gov/pubmed/26693492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/679813
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