Autoimmune Hepatitis in Brazilian Children: IgE and Genetic Polymorphisms in Associated Genes

Pediatric autoimmune hepatitis (AIH) patients present hypergammaglobulinemia, periportal CD8(+) cytotoxic T cell infiltration, and cirrhosis. Autoantibody profile defines AIH types 1 and 2 in addition to strong association with HLA-DRB1. We previously detected increased IgE serum levels and sought t...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: de Oliveira, Léa Campos, Goldberg, Anna Carla, Marin, Maria Lucia Carnevale, Schneidwind, Karina Rosa, Frade, Amanda Farage, Kalil, Jorge, Miura, Irene Kasue, Pugliese, Renata Pereira Sustovich, Danesi, Vera Lucia Baggio, Porta, Gilda
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674601/
https://ncbi.nlm.nih.gov/pubmed/26693492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/679813
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