S-Adenosylhomocysteine induces inflammation through NFkB: a possible role for EZH2 in endothelial cell activation

S-Adenosylhomocysteine (SAH) can induce endothelial dysfunction and activation, contributing to atherogenesis; however, its role in the activation of the inflammatory mediator NFkB has not been explored. Our aim was to determine the role of NFkB in SAH-induced activation of endothelial cells. Furthe...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Barroso, Madalena, Kao, Derrick, Blom, Henk J., de Almeida, Isabel Tavares, Castro, Rita, Loscalzo, Joseph, Handy, Diane E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674364/
https://ncbi.nlm.nih.gov/pubmed/26506125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.10.019
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