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Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project

IMPORTANCE: Stroke is the second leading cause of death and the third leading cause of years of life lost. Genetic factors contribute to stroke prevalence, and candidate gene and genome-wide association studies (GWAS) have identified variants associated with ischemic stroke risk. These variants ofte...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Auer, Paul L., Nalls, Mike, Meschia, James F., Worrall, Bradford B., Longstreth, W. T., Seshadri, Sudha, Kooperberg, Charles, Burger, Kathleen M., Carlson, Christopher S., Carty, Cara L., Chen, Wei-Min, Cupples, L. Adrienne, DeStefano, Anita L., Fornage, Myriam, Hardy, John, Hsu, Li, Jackson, Rebecca D., Jarvik, Gail P., Kim, Daniel S., Lakshminarayan, Kamakshi, Lange, Leslie A., Manichaikul, Ani, Quinlan, Aaron R., Singleton, Andrew B., Thornton, Timothy A., Nickerson, Deborah A., Peters, Ulrike, Rich, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673986/
https://ncbi.nlm.nih.gov/pubmed/25961151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.0582
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