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A cell size- and cell cycle-aware stochastic model for predicting time-dynamic gene network activity in individual cells

BACKGROUND: Despite the development of various modeling approaches to predict gene network activity, a time dynamic stochastic model taking into account real-time changes in cell volume and cell cycle stages is still missing. RESULTS: Here we present a stochastic single-cell model that can be applie...

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Detalles Bibliográficos
Publicado en:BMC Syst Biol
Main Authors: Song, Ruijie, Peng, Weilin, Liu, Ping, Acar, Murat
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673848/
https://ncbi.nlm.nih.gov/pubmed/26646617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0240-5
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