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Aflibercept Traps Galectin-1, an Angiogenic Factor Associated with Diabetic Retinopathy
Vascular endothelial growth factor (VEGF)-A-driven angiogenesis contributes to various disorders including cancer and proliferative diabetic retinopathy (PDR). Among several VEGF-A blockers clinically used is aflibercept, a chimeric VEGFR1/VEGFR2-based decoy receptor fused to the Fc fragment of IgG1...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4673700/ https://ncbi.nlm.nih.gov/pubmed/26648523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17946 |
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