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The lymphocyte secretome from young adults enhances skeletal muscle proliferation and migration, but effects are attenuated in the secretome of older adults

Older people experience skeletal muscle wasting, in part due to impaired proliferative capacity of quiescent skeletal muscle satellite cells which can be reversed by exposure to young blood. To investigate the role of immune cells in muscle regeneration, we isolated lymphocytes from whole blood of y...

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Библиографические подробности
Опубликовано в: :Physiol Rep
Главные авторы: Al-Dabbagh, Sarah, McPhee, Jamie S, Murgatroyd, Christopher, Butler-Browne, Gillian, Stewart, Claire E, Al-Shanti, Nasser
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Ltd 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673618/
https://ncbi.nlm.nih.gov/pubmed/26603449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12518
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