Simplified in vitro engineering of neuromuscular junctions between rat embryonic motoneurons and immortalized human skeletal muscle cells

BACKGROUND: Neuromuscular junctions (NMJs) consist of the presynaptic cholinergic motoneuron terminals and the corresponding postsynaptic motor endplates on skeletal muscle fibers. At the NMJ the action potential of the neuron leads, via release of acetylcholine, to muscle membrane depolarization th...

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Detalles Bibliográficos
Publicado en:Stem Cells Cloning
Autores principales: Saini, Jasdeep, Faroni, Alessandro, Abd Al Samid, Marwah, Reid, Adam J, Lightfoot, Adam P, Mamchaoui, Kamel, Mouly, Vincent, Butler-Browne, Gillian, McPhee, Jamie S, Degens, Hans, Al-Shanti, Nasser
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2019
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388735/
https://ncbi.nlm.nih.gov/pubmed/30863121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/SCCAA.S187655
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