Simplified in vitro engineering of neuromuscular junctions between rat embryonic motoneurons and immortalized human skeletal muscle cells

BACKGROUND: Neuromuscular junctions (NMJs) consist of the presynaptic cholinergic motoneuron terminals and the corresponding postsynaptic motor endplates on skeletal muscle fibers. At the NMJ the action potential of the neuron leads, via release of acetylcholine, to muscle membrane depolarization th...

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Detalhes bibliográficos
Publicado no:Stem Cells Cloning
Main Authors: Saini, Jasdeep, Faroni, Alessandro, Abd Al Samid, Marwah, Reid, Adam J, Lightfoot, Adam P, Mamchaoui, Kamel, Mouly, Vincent, Butler-Browne, Gillian, McPhee, Jamie S, Degens, Hans, Al-Shanti, Nasser
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388735/
https://ncbi.nlm.nih.gov/pubmed/30863121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/SCCAA.S187655
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