Simplified in vitro engineering of neuromuscular junctions between rat embryonic motoneurons and immortalized human skeletal muscle cells

BACKGROUND: Neuromuscular junctions (NMJs) consist of the presynaptic cholinergic motoneuron terminals and the corresponding postsynaptic motor endplates on skeletal muscle fibers. At the NMJ the action potential of the neuron leads, via release of acetylcholine, to muscle membrane depolarization th...

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Bibliographic Details
Published in:Stem Cells Cloning
Main Authors: Saini, Jasdeep, Faroni, Alessandro, Abd Al Samid, Marwah, Reid, Adam J, Lightfoot, Adam P, Mamchaoui, Kamel, Mouly, Vincent, Butler-Browne, Gillian, McPhee, Jamie S, Degens, Hans, Al-Shanti, Nasser
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2019
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388735/
https://ncbi.nlm.nih.gov/pubmed/30863121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/SCCAA.S187655
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