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Energetics of Endotoxin Recognition in the Toll-Like Receptor 4 Innate Immune Response
Bacterial outer membrane lipopolysaccharide (LPS) potently stimulates the mammalian innate immune system, and can lead to sepsis, the primary cause of death from infections. LPS is sensed by Toll-like receptor 4 (TLR4) in complex with its lipid-binding coreceptor MD-2, but subtle structural variatio...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4673606/ https://ncbi.nlm.nih.gov/pubmed/26647780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17997 |
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