The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease

Objective. Activation of membrane receptor guanylate cyclase-C (GC-C) is implicated in gastrointestinal fluid and electrolyte balance, preservation of intestinal barrier integrity, anti-trophic effects and inhibition of pain sensation. To evaluate GC-C signaling, we examined the regulation of GC-C (...

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Publicado en:Scand J Gastroenterol
Autores principales: Brenna, Øystein, Bruland, Torunn, Furnes, Marianne W., Granlund, Atle van Beelen, Drozdov, Ignat, Emgård, Johanna, Brønstad, Gunnar, Kidd, Mark, Sandvik, Arne K., Gustafsson, Björn I.
Formato: Artigo
Lenguaje:Inglês
Publicado: Informa Healthcare 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673555/
https://ncbi.nlm.nih.gov/pubmed/25979109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00365521.2015.1038849
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