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Integrative genomic mining for enzyme function to enable engineering of a non-natural biosynthetic pathway

The ability to biosynthetically produce chemicals beyond what is commonly found in Nature requires the discovery of novel enzyme function. Here we utilize two approaches to discover enzymes that enable specific production of longer-chain (C(5)–C(8)) alcohols from sugar. The first approach combines b...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mak, Wai Shun, Tran, Stephen, Marcheschi, Ryan, Bertolani, Steve, Thompson, James, Baker, David, Liao, James C., Siegel, Justin B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673503/
https://ncbi.nlm.nih.gov/pubmed/26598135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10005
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