Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity

Despite considerable evidence that RNA-binding proteins (RBPs) regulate mRNA transport and local translation in dendrites, roles for axonal RBPs are poorly understood. Here we demonstrate that a non-telomeric isoform of telomere repeat-binding factor 2 (TRF2-S) is a novel RBP that regulates axonal p...

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Pubblicato in:Nat Commun
Autori principali: Zhang, Peisu, Abdelmohsen, Kotb, Liu, Yong, Tominaga-Yamanaka, Kumiko, Yoon, Je-Hyun, Ioannis, Grammatikakis, Martindale, Jennifer L., Zhang, Yongqing, Becker, Kevin G., Yang, In Hong, Gorospe, Myriam, Mattson, Mark P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673492/
https://ncbi.nlm.nih.gov/pubmed/26586091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9888
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