Alternative splicing of neuronal differentiation factor TRF2 regulated by HNRNPH1/H2

During neuronal differentiation, use of an alternative splice site on the rat telomere repeat-binding factor 2 (TRF2) mRNA generates a short TRF2 protein isoform (TRF2-S) capable of derepressing neuronal genes. However, the RNA-binding proteins (RBPs) controlling this splicing event are unknown. Her...

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Vydáno v:Cell Rep
Hlavní autoři: Grammatikakis, Ioannis, Zhang, Peisu, Panda, Amaresh C., Kim, Jiyoung, Maudsley, Stuart, Abdelmohsen, Kotb, Yang, Xiaoling, Martindale, Jennifer L., Motiño, Omar, Hutchison, Emmette R., Mattson, Mark P., Gorospe, Myriam
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856555/
https://ncbi.nlm.nih.gov/pubmed/27117401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.080
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