Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?

Human rhinovirus (HRV) infection is a major cause of asthma exacerbations, which appears to be linked to a defective innate immune response to infection. Although the type I interferons (IFN-α and IFN-β) have a critical role in protecting against most viral infections, the cells responsible for IFN...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Xi, Yang, Finlayson, Arvid, White, Oliva J, Carroll, Melanie L, Upham, John W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673444/
https://ncbi.nlm.nih.gov/pubmed/26682054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2015.27
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