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DNA methylation is stable during replication and cell cycle arrest

DNA methylation is an epigenetic modification with important functions in development. Large-scale loss of DNA methylation is a hallmark of cancer. Recent work has identified large genomic blocks of hypomethylation associated with cancer, EBV transformation and replicative senescence, all of which c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Vandiver, Amy R., Idrizi, Adrian, Rizzardi, Lindsay, Feinberg, Andrew P., Hansen, Kasper D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673417/
https://ncbi.nlm.nih.gov/pubmed/26648411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17911
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