Chargement en cours...
A fully human chimeric antigen receptor with potent activity against cancer cells but reduced risk for off-tumor toxicity
Chimeric antigen receptors (CARs) can redirect T cells against antigen-expressing tumors in an HLA-independent manner. To date, various CARs have been constructed using mouse single chain antibody variable fragments (scFvs) of high affinity that are immunogenic in humans and have the potential to me...
Enregistré dans:
| Publié dans: | Oncotarget |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4673284/ https://ncbi.nlm.nih.gov/pubmed/26101914 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|