NPM1 activates metabolic changes by inhibiting FBP1 while promoting the tumorigenicity of pancreatic cancer cells

The nucleophosmin (NPM1) activates cancer development and progression in many malignant tumors. However, the regulatory role and underlying mechanisms of NPM1 in pancreatic cancer are unknown. In this study, we showed that NPM1 was up-regulated in PDAC, which indicated a poor prognosis. We also iden...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Zhu, Yi, Shi, Minmin, Chen, Hao, Gu, Jiangning, Zhang, Jiaqiang, Shen, Baiyong, Deng, Xiaxing, Xie, Junjie, Zhan, Xi, Peng, Chenghong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673277/
https://ncbi.nlm.nih.gov/pubmed/26068981
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