NPM1 activates metabolic changes by inhibiting FBP1 while promoting the tumorigenicity of pancreatic cancer cells

The nucleophosmin (NPM1) activates cancer development and progression in many malignant tumors. However, the regulatory role and underlying mechanisms of NPM1 in pancreatic cancer are unknown. In this study, we showed that NPM1 was up-regulated in PDAC, which indicated a poor prognosis. We also iden...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Zhu, Yi, Shi, Minmin, Chen, Hao, Gu, Jiangning, Zhang, Jiaqiang, Shen, Baiyong, Deng, Xiaxing, Xie, Junjie, Zhan, Xi, Peng, Chenghong
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673277/
https://ncbi.nlm.nih.gov/pubmed/26068981
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