p53 attenuates AKT signaling by modulating membrane phospholipid composition

The p53 tumor suppressor is the central component of a complex network of signaling pathways that protect organisms against the propagation of cells carrying oncogenic mutations. Here we report a previously unrecognized role of p53 in membrane phospholipids composition. By repressing the expression...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Rueda-Rincon, Natalia, Bloch, Katarzyna, Derua, Rita, Vyas, Rajesh, Harms, Amy, Hankemeier, Thomas, Khan, Niamat Ali, Dehairs, Jonas, Bagadi, Muralidhararao, Binda, Maria Mercedes, Waelkens, Etienne, Marine, Jean-Christophe, Swinnen, Johannes V.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673262/
https://ncbi.nlm.nih.gov/pubmed/26061814
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