RTVP-1 promotes mesenchymal transformation of glioma via a STAT-3/IL-6-dependent positive feedback loop

Glioblastomas (GBMs), the most aggressive primary brain tumors, exhibit increased invasiveness and resistance to anti-tumor treatments. We explored the role of RTVP-1, a glioma-associated protein that promotes glioma cell migration, in the mesenchymal transformation of GBM. Analysis of The Cancer Ge...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Giladi, Nis David, Ziv-Av, Amotz, Lee, Hae Kyung, Finniss, Susan, Cazacu, Simona, Xiang, Cunli, Ben-Asher, Hiba Waldman, deCarvalho, Ana, Mikkelsen, Tom, Poisson, Laila, Brodie, Chaya
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673191/
https://ncbi.nlm.nih.gov/pubmed/26267319
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