Intact LKB1 activity is required for survival of dormant ovarian cancer spheroids

Metastatic epithelial ovarian cancer (EOC) cells can form multicellular spheroids while in suspension and disperse directly throughout the peritoneum to seed secondary lesions. There is growing evidence that EOC spheroids are key mediators of metastasis, and they use specific intracellular signallin...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Peart, Teresa, Valdes, Yudith Ramos, Correa, Rohann J. M., Fazio, Elena, Bertrand, Monique, McGee, Jacob, Préfontaine, Michel, Sugimoto, Akira, DiMattia, Gabriel E., Shepherd, Trevor G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673173/
https://ncbi.nlm.nih.gov/pubmed/26068970
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