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Polylactide-based Paclitaxel-loaded Nanoparticles Fabricated by Dispersion Polymerization: Characterization, Evaluation in Cancer Cell Lines, and Preliminary Biodistribution Studies

The macromonomer method was used to prepare crosslinked, paclitaxel-loaded polylactide-polyethylene glycol (stealth) nanoparticles using free-radical dispersion polymerization. The method can facilitate the attachment of other molecules to the nanoparticle surface to make it multifunctional. Proton...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Adesina, Simeon K., Holly, Alesia, Kramer-Marek, Gabriela, Capala, Jacek, Akala, Emmanuel O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672948/
https://ncbi.nlm.nih.gov/pubmed/24961596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24061
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