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Applications of Cas9 as an RNA-programmed RNA-binding protein

The Streptococcus pyogenes CRISPR-Cas system has gained widespread application as a genome editing and gene regulation tool as simultaneous cellular delivery of the Cas9 protein and guide RNAs enables recognition of specific DNA sequences. The recent discovery that Cas9 can also bind and cleave RNA...

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Detalles Bibliográficos
Publicado en:Bioessays
Main Authors: Nelles, David A., Fang, Mark Y., Aigner, Stefan, Yeo, Gene W.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672944/
https://ncbi.nlm.nih.gov/pubmed/25880497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500001
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