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Applications of Cas9 as an RNA-programmed RNA-binding protein

The Streptococcus pyogenes CRISPR-Cas system has gained widespread application as a genome editing and gene regulation tool as simultaneous cellular delivery of the Cas9 protein and guide RNAs enables recognition of specific DNA sequences. The recent discovery that Cas9 can also bind and cleave RNA...

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Bibliografski detalji
Izdano u:Bioessays
Glavni autori: Nelles, David A., Fang, Mark Y., Aigner, Stefan, Yeo, Gene W.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672944/
https://ncbi.nlm.nih.gov/pubmed/25880497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500001
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