Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid

Human β-defensin 3 (hBD3) is a cationic host defence peptide and is part of the innate immune response. HBD3 is present on a highly copy number variable block of six β-defensin genes, and increased copy number is associated with the autoimmune disease psoriasis. It is not known how this increase inf...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Semple, Fiona, MacPherson, Heather, Webb, Sheila, Kilanowski, Fiona, Lettice, Laura, McGlasson, Sarah L., Wheeler, Ann P., Chen, Valerie, Millhauser, Glenn L., Melrose, Lauren, Davidson, Donald J., Dorin, Julia R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672878/
https://ncbi.nlm.nih.gov/pubmed/26646717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005673
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados