Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity

Excitatory amino acids play a key role in both adaptive and deleterious effects of stressors on the brain, and dysregulated glutamate homeostasis has been associated with psychiatric and neurological disorders. Here, we elucidate mechanisms of epigenetic plasticity in the hippocampus in the interact...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Nasca, Carla, Zelli, Danielle, Bigio, Benedetta, Piccinin, Sonia, Scaccianoce, Sergio, Nisticò, Robert, McEwen, Bruce S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672825/
https://ncbi.nlm.nih.gov/pubmed/26627246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516016112
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