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Parkin structure and function

Mutations in the parkin or PINK1 genes are the leading cause of the autosomal recessive form of Parkinson’s disease. The gene products, the E3 ubiquitin ligase parkin and the serine/threonine kinase PINK1, are neuroprotective proteins, which act together in a mitochondrial quality control pathway. H...

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Dades bibliogràfiques
Publicat a:FEBS J
Autors principals: Seirafi, Marjan, Kozlov, Guennadi, Gehring, Kalle
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672691/
https://ncbi.nlm.nih.gov/pubmed/25712550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13249
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