Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J(2) on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis

OBJECTIVE: 15-Deoxy-Δ12,14-prostaglandin J(2) (15d-PGJ(2)) induces reactive oxygen species (ROS)-mediated apoptosis in many malignant cells, which has not been studied in hepatoma cells. In this study, we investigated whether 15d-PGJ(2) induced apoptosis in hepatocellular carcinoma (HCC) associated...

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Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Chen, Kan, Dai, Weiqi, Wang, Fan, Xia, Yujing, Li, Jingjing, Li, Sainan, Liu, Tong, Zhang, Rong, Wang, Jianrong, Lu, Wenxia, Zhou, Yuqing, Yin, Qin, Zheng, Yuanyuan, Abudumijiti, Huerxidan, Chen, Rongxia, Lu, Jie, Zhou, Yingqun, Guo, Chuanyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671813/
https://ncbi.nlm.nih.gov/pubmed/26664142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S92832
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