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The relationship between UGT1A1 gene polymorphism and irinotecan effect on extensive-stage small-cell lung cancer

AIMS: To analyze the distribution of uridine diphosphate glucuronosyltransferase (UGT)1A1 gene polymorphisms in Chinese patients with extensive-stage small-cell lung cancer (E-SCLC), and to evaluate correlations between the UGT1A1 gene polymorphisms and toxicity, and efficacy of irinotecan (CPT-11)...

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Enregistré dans:
Détails bibliographiques
Publié dans:Onco Targets Ther
Auteurs principaux: Xiao, Xiao-guang, Xia, Shu, Zou, Man, Mei, Qi, Zhou, Lei, Wang, Shu-jing, Chen, Yuan
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671801/
https://ncbi.nlm.nih.gov/pubmed/26664141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S95149
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