Relationship between UGT1A1*27 and UGT1A1*7 polymorphisms and irinotecan‐related toxicities in patients with lung cancer

BACKGROUND: The objective of this study was to evaluate the effects of gene polymorphisms, including UGT1A1*7, *27, and *29, on the safety of irinotecan therapy. METHODS: The eligibility criteria were: lung cancer patients scheduled to undergo irinotecan therapy, aged ≥ 20 years, with a performance...

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Detalhes bibliográficos
Publicado no:Thorac Cancer
Main Authors: Fukuda, Minoru, Okumura, Manabu, Iwakiri, Tomomi, Arimori, Kazuhiko, Honda, Takuya, Kobayashi, Kazuma, Senju, Hiroaki, Takemoto, Shinnosuke, Ikeda, Takaya, Yamaguchi, Hiroyuki, Nakatomi, Katsumi, Matsuo, Nobuko, Mukae, Hiroshi, Ashizawa, Kazuto
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Australia, Ltd 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754284/
https://ncbi.nlm.nih.gov/pubmed/29052349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.12535
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